MYCi975 New
Data Sheet
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| CAS No. | 2289691-01-4 | Cat. No. | BCP34062 |
| Name | MYCi975 | ||
| Synonyms | MYCi-975;MYCi 975;NUCC-0200975;NUCC 0200975;NUCC0200975; | ||
| SMILES | CN1C(=CC(=N1)C(F)(F)F)C2=C(C(=C(C=C2)OCC3=CC=C(C=C3)Cl)C4=CC(=C(C=C4)Cl)C(F)(F)F)O | ||
| Chemical Name | |||
| Formula | C25H16Cl2F6N2O2 | M. Wt | 561.30 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | MYCi975 is an orally active MYC inhibitor, which disrupts MYC/MAX interaction, promotes MYC T58 phosphorylation and MYC degradation, and impairs MYC driven gene expression. MYCi975 (NUCC-0200975) exhibits potent anti-tumor efficacy with good tolerability, increases tumor immune cell infiltration, and sensitizes tumors to anti-PD1 immunotherapy. | ||
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