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CAS No. | 403811-55-2 | Cat. No. | BCP08097 |
Name | 10058-F4 | ||
Synonyms | 10058F4; 10058 F4; | ||
SMILES | CCC1=CC=C(C=C1)C=C2C(=O)NC(=S)S2 | ||
Chemical Name | |||
Formula | C12H11NOS2 | M. Wt | 249.35 |
Purity | 98% | Storage | Store at 4-8°C |
Description | 10058-F4 is a potent and selective c-Myc inhibitor, which markedly increases valproic acid-induced cell death in Jurkat and CCRF-CEM T-lymphoblastic leukemia cells. 10058-F4 inhibits proliferation, downregulates human telomerase reverse transcriptase and enhances chemosensitivity in human hepatocellular carcinoma cells. 10058-F4 induces cell-cycle arrest, apoptosis, and myeloid differentiation of human acute myeloid leukemia. |
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