Snail/HDAC-IN-1 New
Data Sheet
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| CAS No. | 2415281-52-4 | Cat. No. | BCP48514 |
| Name | Snail/HDAC-IN-1 | ||
| Synonyms | CYD19; | ||
| SMILES | CC1=CC(=NN1)NC2=NC(=NN3C2=CC=C3)SCC4=CC=C(C=C4)C(=O)NC5=C(C=C(C=C5)F)N | ||
| Chemical Name | |||
| Formula | C24H21FN8OS | M. Wt | 488.54 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Snail/HDAC-IN-1 is a potent Snail/HDAC dual target inhibitor. Snail/HDAC-IN-1 displays potent inhibitory activity against HDAC1 with an IC50 of 0.405 μM and potent inhibition against Snail with a Kd of 0.18 μM. Snail/HDAC-IN-1 increases histone H4 acetylation in HCT-116 cells and decreases the expression of Snail protein to induce cell apoptosis. | ||
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