Pracinostat Dihydrochloride New
Data Sheet
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| CAS No. | 929016-98-8 | Cat. No. | BCP43352 |
| Name | Pracinostat Dihydrochloride | ||
| Synonyms | Pracinostat 2HCl; Fezolinetant; ESN-364; ESN 364; ESN364; | ||
| SMILES | CCCCC1=NC2=C(N1CCN(CC)CC)C=CC(=C2)C=CC(=O)NO.Cl.Cl | ||
| Chemical Name | |||
| Formula | C20H32Cl2N4O2 | M. Wt | 431.4 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Pracinostat, also known as SB939, is an orally bioavailable, small-molecule histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. Pracinostat inhibits HDACs, which may result in the accumulation of highly acetylated histones, followed by the induction of chromatin remodeling; the selective transcription of tumor suppressor genes; the tumor suppressor protein-mediated inhibition of tumor cell division; and, finally, the induction of tumor cell apoptosis. | ||
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