Fosaprepitant dimeglumine New
Data Sheet
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| CAS No. | 265121-04-8 | Cat. No. | BCP05167 |
| Related Products | 172673-20-0（Fosaprepitant） | ||
| Name | Fosaprepitant dimeglumine | ||
| Synonyms | MK-0517 dimeglumine; MK0517 dimeglumine; MK 0517 dimeglumine; | ||
| SMILES | CC(C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)OC2C(N(CCO2)CC3=NC(=O)N(N3)P(=O)(O)O)C4=CC=C(C=C4)F.CNCC(C(C(C(CO)O)O)O)O.CNCC(C(C(C(CO)O)O)O)O | ||
| Chemical Name | |||
| Formula | C23H22F7N4O6P·2C7H17NO5 | M. Wt | 1004.84 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Fosaprepitant Dimeglumine is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion to aprepitant, this agent binds selectively to the human substance P/neurokinin 1 (NK1) receptors in the central nervous system (CNS). This inhibits receptor binding of the endogenous substance P and prevents substance P-induced emesis. | ||
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