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Pavinetant Chemical Structure

Pavinetant

Data Sheet For research use only. Not for human use.
Cat. No. :BCP48976CAS No. :941690-55-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 941690-55-7 Cat. No. BCP48976
Name Pavinetant
Synonyms AZD-2624; AZD2624; AZD 2624; MLE-4901; MLE4901; MLE 4901; AZD-4901; AZD 4901; AZD4901; AZ-12472520; AZ 12472520; AZ12472520;
SMILES CCC(C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)NS(=O)(=O)C
Chemical Name
Formula C26H25N3O3S M. Wt 459.56
Purity 98% Storage Store at 4-8°C
Description Pavinetant is a small-molecule, orally active, selective neurokinin-3 (NK3) receptor antagonist which is under development by AstraZeneca and Millendo Therapeutics for the treatment of hot flashes and polycystic ovary syndrome (PCOS). It was also under investigation for the treatment of schizophrenia, but development was discontinued for this indication due to lack of effectiveness. As of 2017, the drug is in phase II clinical trials for hot flashes and PCOS.
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