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CITCO Chemical Structure

CITCO

Data Sheet For research use only. Not for human use.
Cat. No. :BCP43367CAS No. :338404-52-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 338404-52-7 Cat. No. BCP43367
Name CITCO
Synonyms CITCO;
SMILES C1=CC(=CC=C1C2=C(N3C=CSC3=N2)C=NOCC4=CC(=C(C=C4)Cl)Cl)Cl
Chemical Name
Formula C19H12Cl3N3OS M. Wt 436.74
Purity 98% Storage Store at 4-8°C
Description CITCO, an imidazothiazole derivative, is a selective Constitutive androstane receptor (CAR) agonist. CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear receptors.
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