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CAS No. | 338404-52-7 | Cat. No. | BCP43367 |
Name | CITCO | ||
Synonyms | CITCO; | ||
SMILES | C1=CC(=CC=C1C2=C(N3C=CSC3=N2)C=NOCC4=CC(=C(C=C4)Cl)Cl)Cl | ||
Chemical Name | |||
Formula | C19H12Cl3N3OS | M. Wt | 436.74 |
Purity | 98% | Storage | Store at 4-8°C |
Description | CITCO, an imidazothiazole derivative, is a selective Constitutive androstane receptor (CAR) agonist. CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear receptors. |
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