LM22B-10 New
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CAS No. | 342777-54-2 | Cat. No. | BCP30139 |
Name | LM22B-10 | ||
Synonyms | LM22B 10; LM22B10; LM 22B10; LM-22B10; LM22B10; | ||
SMILES | C1=CC(=CC=C1C(C2=CC=C(C=C2)N(CCO)CCO)C3=CC=C(C=C3)Cl)N(CCO)CCO | ||
Chemical Name | |||
Formula | C27H33ClN2O4 | M. Wt | 485.02 |
Purity | 98% | Storage | Store at 4-8°C |
Description | LM22B-10 is a TrkB and TrkC agonist. LM22B-10 exhibits neurotrophic activity (EC50 = 200-300 nM). LM22B-10 improves survival and increases neurite outgrowth in hippocampal cells in vitro. LM22B-10 increased cell survival and strongly accelerated neurite outgrowth, superseding the effects of brain-derived neurotrophic factor (BDNF), NT-3 or the two combined. |
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