Lapatinib Ditosylate New
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| CAS No. | 388082-78-8 | Cat. No. | BCP01815 |
| Related Products | 231277-92-2（Lapatinib） 388082-77-7（Lapatinib ditosylate） | ||
| Name | Lapatinib Ditosylate | ||
| Synonyms | Tykerb Ditosylate;GW572016 ditosylate; GW2016 ditosylate; | ||
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl | ||
| Chemical Name | |||
| Formula | C29H26ClFN4O4S.2(C7H8O3S) | M. Wt | 925.46 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Lapatinib Ditosylate is the ditosylate salt of lapatinib, a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types. | ||
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