CUDC-101 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1012054-59-9 | Cat. No. | BCP01935 |
| Name | CUDC-101 | ||
| Synonyms | CUDC101;CUDC 101; | ||
| SMILES | COC1=C(C=C2C(=C1)N=CN=C2NC3=CC=CC(=C3)C#C)OCCCCCCC(=O)NO | ||
| Chemical Name | |||
| Formula | C24H26N4O4 | M. Wt | 434.49 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | CUDC-101 is a multi-targeted, small-molecule inhibitor of histone deacetylase (HDAC), epidermal growth factor receptor tyrosine kinase (EGFR/ErbB1), and human epidermal growth factor receptor 2 tyrosine kinase (HER2/neu or ErbB2) with potential antineoplastic activity. HDAC/EGFR/HER2 inhibitor CUDC-101 inhibits the activity of these three enzymes but the exact mechanism of action is presently unknown. This agent may help overcome resistance to inhibition of EGFR and Her2 through a simultaneous, synergistic inhibition of EGFR, Her2, and HDAC. | ||
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