SB-681323
Data Sheet
For research use only. Not for human use.
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| CAS No. | 444606-18-2 | Cat. No. | BCP23819 |
| Name | SB-681323 | ||
| Synonyms | SB 681323; SB681323; GW 681323; GW-681323; GW681323; Dilmapimod; | ||
| SMILES | O=C1C=CC2=C(C3=CC=C(F)C=C3C)N=C(NC(CO)CO)N=C2N1C4=C(F)C=CC=C4F | ||
| Chemical Name | |||
| Formula | C23H19F3N4O3 | M. Wt | 456.42 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | SB-681323, also known as Dilmapimod and GW-681323 , is p38 MAPK inhibitor. SB-681323 inhibited the p38 MAPK pathway to a greater degree than prednisolone did. SB-681323 inhibited TNF-alpha production. SB-681323 is a potent p38 MAPK inhibitor that potentially suppresses inflammation in COPD. The treatment with SB-681832 is a safe and effective means of reducing hsCRP in patients undergoing elective PCI. | ||
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