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SB 203580 hydrochloride Chemical Structure

SB 203580 hydrochloride

Data Sheet For research use only. Not for human use.
Cat. No. :BCP29070CAS No. :869185-85-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 869185-85-3 Cat. No. BCP29070
Name SB 203580 hydrochloride
Synonyms RWJ 64809 hydrochloride;RWJ64809 HCl;SB203580 HCl;
SMILES CS(=O)C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F.Cl
Chemical Name
Formula C21H17ClFN3OS M. Wt 413.9
Purity 98% Storage Store at 4-8°C
Description SB 203580 hydrochloride is a water-soluble form of the potent MAP kinase inhibitor SB 203580 with IC50 values of 50 and 500 nM for SAPK2a/p38 and SAPK2b/p38β2, respectively. It was shown to inhibit interleukin-2-induced T cell proliferation, cyclooxygenase-1 and -2, and thromboxane synthase.
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