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CAS No. | 869185-85-3 | Cat. No. | BCP29070 |
Name | SB 203580 hydrochloride | ||
Synonyms | RWJ 64809 hydrochloride;RWJ64809 HCl;SB203580 HCl; | ||
SMILES | CS(=O)C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F.Cl | ||
Chemical Name | |||
Formula | C21H17ClFN3OS | M. Wt | 413.9 |
Purity | 98% | Storage | Store at 4-8°C |
Description | SB 203580 hydrochloride is a water-soluble form of the potent MAP kinase inhibitor SB 203580 with IC50 values of 50 and 500 nM for SAPK2a/p38 and SAPK2b/p38β2, respectively. It was shown to inhibit interleukin-2-induced T cell proliferation, cyclooxygenase-1 and -2, and thromboxane synthase. |
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