2-Methylthioadenosine diphosphate trisodium salt New
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CAS No. | 475193-31-8 | Cat. No. | BCP42041 |
Name | 2-Methylthioadenosine diphosphate trisodium salt | ||
Synonyms | 2-(Methylthio)adenosine 5'-diphosphate sodium salt; | ||
SMILES | CSC1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])[O-])O)O)N.[Na+].[Na+].[Na+] | ||
Chemical Name | |||
Formula | C11H14N5Na3O10P2S | M. Wt | 539.24 |
Purity | 98% | Storage | Store at 4-8°C |
Description | 2-Methylthioadenosine diphosphate trisodium salt is a potent purinergic agonist displaying selectivity for P2Y1, P2Y12 and P2Y13 receptors (pEC50 = 8.29 and 9.05 for P2Y1 and P2Y12, EC50 = 19 nM for P2Y13), which induces platelet aggregation and shape change and inhibits cyclic AMP accumulation in platelets exposed to prostaglandin E1. |
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