BAL27862
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CAS No. | 798577-91-0 | Cat. No. | BCP16476 |
Name | BAL27862 | ||
Synonyms | BAL-27862;BAL 27862; | ||
SMILES | |||
Chemical Name | |||
Formula | C20H17N7O2 | M. Wt | 387.39 |
Purity | 98% | Storage | Store at 4-8°C |
Description | BAL27862 is a a novel synthetic potent inhibitor of tubulin polymerization that induces cancer cell death. BAL27862 is a novel microtubule-destabilizing drug that is currently undergoing phase I clinical evaluation as the prodrug BAL101553. BAL27862 elicits a unique microtubule (MT) phenotype, distinct from paclitaxel, vinblastine and colchicine, has broad in vitro anti-proliferative activity against a diverse range of human tumor lines (low nM IC50s) and induces significant antitumor responses in a range |
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