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Encequidar Chemical Structure

Encequidar

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP25240CAS No. ：849675-66-7Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 849675-66-7 Cat. No. BCP25240
Related Products 849675-87-2（Encequidar mesylate） 2097125-58-9（Encequidar mesylate monohydrate）
Name Encequidar
Synonyms HM30181 ;HM-30181; HM 30181;HM-30181-A; HM30181A;
SMILES
Chemical Name
Formula C38H36N6O7 M. Wt 688.73
Purity 98% Storage Store at 4-8°C
Description Encequidar, also known as HM-30181, is an oral P-glycoprotein (P-gp) inhibitor developed to enhance the oral bioavailability of P-gp substrate drugs. Encequidar showed the highest potency (IC(50)=0.63nM) among several MDR1 inhibitors, including cycloporin A, XR9576, and GF120918, and effectively blocked transepithelial transport of paclitaxel in MDCK monolayers (IC(50)=35.4nM). Encequidar is currently under clinical trials.
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