Niclosamide New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 50-65-7 | Cat. No. | BCP22958 |
| Name | Niclosamide | ||
| Synonyms | Niclocide;BAY 2353; NSC 178296; WR 46234; BAY-2353; NSC-178296; WR-46234; BAY2353; NSC178296; WR46234; | ||
| SMILES | C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O | ||
| Chemical Name | |||
| Formula | C13H8Cl2N2O4 | M. Wt | 327.12 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Niclosamide is an oral antihelminthic drug, which has been used to treat tapeworm infection for about 50 years. Niclosamide is also used as a molluscicide for water treatment in schistosomiasis control programs. Recently, several groups have independently discovered that niclosamide is also active against cancer cells. Evidence supports that niclosamide targets multiple signaling pathways (NF-κB, Wnt/β-catenin, Notch, ROS, mTORC1, and Stat3), most of which are closely involved with cancer stem cells. Given its potential antitumor activity, clinical trials for niclosamide and its derivatives are warranted for cancer treatment. | ||
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