JI-101
Data Sheet
For research use only. Not for human use.
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| CAS No. | 900573-88-8 | Cat. No. | BCP16892 |
| Name | JI-101 | ||
| Synonyms | JI 101;JI101; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C22H20BrN5O2 | M. Wt | 466.33 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Angiogenesis inhibitor JI-101 binds to and inhibits VEGFR2, PDGFRb and EphB4, which may inhibit tumor angiogenesis and, so, cellular proliferation in tumor cells overexpressing VEGFR2, PDGFRb and EphB4. The receptor tyrosine kinases VEGFR2, PDGFRb and EphB4 may be overexpressed in a number of different cancer cell types and may play crucial roles in tumor angiogenesis. Check for active clinical trials or closed clinical trials using this agent. | ||
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