Gusacitinib HCl New

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP31676CAS No. ：GusacitinibHClPurity：98%

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Chemical Properties&Biological Activity

CAS No.	GusacitinibHCl	Cat. No.	BCP31676
Name	Gusacitinib HCl
Synonyms	ASN002 hydrochloride; ASN002 HCl;ASN-002 HCl;ASN 002 HCl;
SMILES
Chemical Name
Formula	C24H29ClN8O2	M. Wt	497.00
Purity	98%	Storage	Store at 4-8°C
Description	Gusacitinib is a potent dual inhibitor of SYK/JAK kinases. ASN002 showed strong antitumor activity in both hematological and solid tumor xenograft models. ASN002 strongly suppressed the SYK and JAK family kinase signaling pathways as measured in pLAT and pSTAT assays, respectively. When profiled in a panel of 178 cell lines, ASN002 showed strong anti-proliferative activity in many lymphoid/leukemia cell lines, including SU-DHL-6, SU-DHL-4, OCI-LY10, H929 and Pfeiffer.

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