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CAS No. | 1026134-63-3 | Cat. No. | BCP32806 |
Name | Nelonicline | ||
Synonyms | ABT-126; ABT126; ABT 126; | ||
SMILES | C1C2CC3CN(C2)CC1C3OC4=NN=C(S4)C5=CC=CC=C5 | ||
Chemical Name | |||
Formula | C17H19N3OS | M. Wt | 313.42 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Nelonicline, aslo known as ABT-126, is an Alpha7 nicotinic acetylcholine receptor agonist and Nicotinic acetylcholine receptor agonist. Nelonicline is potentially useful for the treatment of Alzheimer's diseases. ABT-126 may be useful to reduce dyskinesias in both early- and later-stage Parkinson's disease. Accumulating evidence suggests that the α7 subtype of nicotinic acetylcholine receptors (nAChRs) plays a key role in inflammatory processes, thought to be involved in the pathophysiology of neuropsychiatric diseases, such as schizophrenia and Alzheimer's disease. |
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