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Anagyrin Chemical Structure

Anagyrin

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP44368CAS No. ：486-89-5Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 486-89-5 Cat. No. BCP44368
Name Anagyrin
Synonyms Monolupine;Rhombinine;
SMILES C1CCN2CC3CC(C2C1)CN4C3=CC=CC4=O
Chemical Name
Formula C15H20N2O M. Wt 244.33
Purity 98% Storage Store at 4-8°C
Description Anagyrine is an alkaloid that has been found in L. albus and has nematocidal and anticancer activities. It binds to muscarinic and nicotinic acetylcholine receptors with IC50 values of 132 and 2,096 µM, respectively, in radioligand binding assays using pig brain membranes that endogenously express high levels of the receptors. Anagyrine decreases survival of B. xylophilus worms. It inhibits proliferation of TE-671 and SH-SY5Y cancer cells. Maternal ingestion of anagyrine during gestation is associated with the teratogenic condition crooked calf disease in cattle.
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