PNU-282987 S enantiomer free base New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 737727-12-7 | Cat. No. | BCP25435 |
| Name | PNU-282987 S enantiomer free base | ||
| Synonyms | |||
| SMILES | C1CN2CCC1C(C2)NC(=O)C3=CC=C(C=C3)Cl | ||
| Chemical Name | |||
| Formula | C14H17ClN2O | M. Wt | 264.75 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | PNU-282987 is a highly selective α7 nAChR agonist (Ki = 26 nM) displaying negligible blockade of α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM). PNU-282987 is inactive against a panel of 32 receptors at 1 μM, except 5-HT3 receptors (Ki = 930 nM). | ||
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