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PNU-282987 S enantiomer free base Chemical Structure

PNU-282987 S enantiomer free base

Data Sheet For research use only. Not for human use.
Cat. No. :BCP25435CAS No. :737727-12-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 737727-12-7 Cat. No. BCP25435
Name PNU-282987 S enantiomer free base
Synonyms
SMILES C1CN2CCC1C(C2)NC(=O)C3=CC=C(C=C3)Cl
Chemical Name
Formula C14H17ClN2O M. Wt 264.75
Purity 98% Storage Store at 4-8°C
Description PNU-282987 is a highly selective α7 nAChR agonist (Ki = 26 nM) displaying negligible blockade of α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM). PNU-282987 is inactive against a panel of 32 receptors at 1 μM, except 5-HT3 receptors (Ki = 930 nM).
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