PSEM 89S TFA New

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP35173CAS No. ：1336913-03-1Purity：98%

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Chemical Properties&Biological Activity

CAS No.	1336913-03-1	Cat. No.	BCP35173
Name	PSEM 89S TFA
Synonyms	PSEM 89S;
SMILES	COC1=CC(=C(C=C1)OC)C(=O)NC2CN3CCC2CC3.C(=O)(C(F)(F)F)O
Chemical Name
Formula	C18H23F3N2O5	M. Wt	404.39
Purity	98%	Storage	Store at 4-8°C
Description	PSEM 89S TFA is a PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist (EC50 values are 3.4 and 2.2 μM, respectively). Activates cortical neurons expressing PSAML141F,Y115F-5-HT3 chimeric ion channels and inhibits activity of neurons expressing PSAML141F-GlyR in vitro. Silences hypothalamic AGRP neurons transfected with PSAML141F-GlyR chimeric ion channels in mice in vivo, leading to suppression of feeding. Brain penetrant.

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