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CAS No. | 1375466-18-4 | Cat. No. | BCP30179 |
Name | ACY-775 | ||
Synonyms | ACY 775; ACY775; | ||
SMILES | C1CCC(CC1)(C2=CC(=CC=C2)F)NC3=NC=C(C=N3)C(=O)NO | ||
Chemical Name | |||
Formula | C17H19FN4O2 | M. Wt | 330.36 |
Purity | 98% | Storage | Store at 4-8°C |
Description | ACY-775 is a potent and selective HDAC6 inhbiitor. ACY-775 inhibits HDAC6 with low nanomolar potency and a selectivity of 60- to 1500-fold over class I HDACs. ACY-775 shares the antidepressant-like properties of other HDAC inhibitors, such as SAHA and MS-275, in the tail suspension test and social defeat paradigm. |
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