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CAS No. | 1496510-51-0 | Cat. No. | BCP30640 |
Name | Relacorilant | ||
Synonyms | CORT125134; CORT-125134; CORT 125134; | ||
SMILES | CN1C=C(C=N1)S(=O)(=O)N2CCC3=CC4=C(CC3(C2)C(=O)C5=NC=CC(=C5)C(F)(F)F)C=NN4C6=CC=C(C=C6)F | ||
Chemical Name | |||
Formula | C27H22F4N6O3S | M. Wt | 586.56 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Relacorilant is a potent, selective and orally bioavailable glucocorticoid receptor antagonist, with a Ki of 7.2 nM in HepG2 TAT assay, and also shows Kis of 12, 81.2, 210 nM for rat, human and monkey glucocorticoid receptor in cell-based assay, respectively; Relacorilant has entered phase 2 clinical study in patients with Cushing’s syndrome. |
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