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Relacorilant Chemical Structure

Relacorilant

Data Sheet For research use only. Not for human use.
Cat. No. :BCP30640CAS No. :1496510-51-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1496510-51-0 Cat. No. BCP30640
Name Relacorilant
Synonyms CORT125134; CORT-125134; CORT 125134;
SMILES CN1C=C(C=N1)S(=O)(=O)N2CCC3=CC4=C(CC3(C2)C(=O)C5=NC=CC(=C5)C(F)(F)F)C=NN4C6=CC=C(C=C6)F
Chemical Name
Formula C27H22F4N6O3S M. Wt 586.56
Purity 98% Storage Store at 4-8°C
Description Relacorilant is a potent, selective and orally bioavailable glucocorticoid receptor antagonist, with a Ki of 7.2 nM in HepG2 TAT assay, and also shows Kis of 12, 81.2, 210 nM for rat, human and monkey glucocorticoid receptor in cell-based assay, respectively; Relacorilant has entered phase 2 clinical study in patients with Cushing’s syndrome.
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