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CAS No. | 2443816-45-1 | Cat. No. | BCP37780 |
Name | ULK-101 | ||
Synonyms | ULK 101; ULK101; | ||
SMILES | C1CC1C(C(F)(F)F)NC(=O)C2=CC(=CS2)C3=C4N=CC(=CN4N=C3)C5=CC=C(C=C5)F | ||
Chemical Name | |||
Formula | C22H16F4N4OS | M. Wt | 460.45 |
Purity | 98% | Storage | Store at 4-8°C |
Description | ULK-101 is a potent and selective ULK1 inhibitor with in vitro IC50 of 8.3 nM. ULK-101 suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress. ULK-101 represents a powerful molecular tool to study the role of autophagy in cancer cells and to evaluate the therapeutic potential of autophagy inhibition. |
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