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Upamostat Chemical Structure

Upamostat

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP23974CAS No. ：590368-25-5Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 590368-25-5 Cat. No. BCP23974
Name Upamostat
Synonyms WX 671;WX671;WX-671;Mesupron;
SMILES O=C(N1CCN(C([C@@H](NS(=O)(C2=C(C(C)C)C=C(C(C)C)C=C2C(C)C)=O)CC3=CC=CC(C(NO)=N)=C3)=O)CC1)OCC
Chemical Name
Formula C32H47N5O6S M. Wt 629.81
Purity 98% Storage Store at 4-8°C
Description Upamostat, also known as Mesupron and WX-671, is an orally bioavailable, 3-amidinophenylalanine-derived, second generation serine protease inhibitor prodrug targeting the human urokinase plasminogen activator (uPA) system with potential antineoplastic and antimetastatic activities. After oral administration, serine protease inhibitor WX-671 is converted to the active Nα-(2,4,6-triisopropylphenylsulfonyl)-3-amidino-(L)-phenyla lanine-4-ethoxycarbonylpiperazide (WX-UK1), which inhibits several serine proteases, particularly uPA; inhibition of uPA may result in the inhibition of tumor growth and metastasis.
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