Flumatinib mesylate
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 895519-91-2 | Cat. No. | BCP08647 |
| Name | Flumatinib mesylate | ||
| Synonyms | HHGV678 mesylate; HHGV 678 mesylate ; HHGV-678 mesylate; HH-GV-678 mesylate; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C30H33F3N8O4S | M. Wt | 658.69 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Flumatinib Mesylate is the orally bioavailable, mesylate salt form of the tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity. Upon administration, flumatinib inhibits the wild-type forms of Bcr-Abl, platelet-derived growth factor receptor (PDGFR) and mast/stem cell growth factor receptor (SCFR; c-Kit) and forms of these proteins with certain point mutations. This results in the inhibition of both Bcr-Abl-, PDGFR- and c-Kit-mediated signal transduction pathways, and the proliferation of tumor cells in which these kinases are overexpressed. Bcr-Abl fusion protein is an abnormal, constitutively active enzyme expressed in Philadelphia chromosome positive chronic myeloid leukemia (CML), acute lymphoblastic leukemia (ALL) or acute myelogenous leukemia (AML). PDGFR, upregulated in many tumor cell types, is a receptor tyrosine kinase essential to cell migration and the development of the microvasculature. c-kit, a receptor tyrosine kinase mutated and constitutively activated in certain tumors, plays a key role in tumor cell survival, proliferation, and differentiation. | ||
Recommend Products
More >
-
-
Vodobatinib
Cat. No.：BCP43522
No.：1388803-90-4
Product Details -
Elzovantinib
Cat. No.：BCP40929
No.：2271119-26-5
Product Details -
-
DGY-06-116
Cat. No.：BCP37659
No.：2556836-50-9
Product Details -
PD173955-Analog1
Cat. No.：BCP36116
No.：185039-99-0
Product Details -
CH6953755
Cat. No.：BCP35548
No.：2055918-71-1
Product Details -
-
-
Saracatinib difumarate
Cat. No.：BCP25711
No.：893428-72-3
Product Details -
KX2-391 Mesylate
Cat. No.：BCP25173
No.：1080645-95-9
Product Details -
Src Kinase Inhibitor I
Cat. No.：BCP24909
No.：179248-59-0
Product Details -
Tyrphostin AG 1112
Cat. No.：BCP24145
No.：153150-84-6
Product Details -
-
-
-
pp60c-src Fragment 521-533
Cat. No.：BCP27682
No.：149299-77-4
Product Details -
PD 166285 dihydrochloride
Cat. No.：BCP22349
No.：212391-63-4
Product Details -
-
TG 100572 Hydrochloride
Cat. No.：BCP21364
No.：867331-64-4
Product Details
Tags:Flumatinib mesylate supplier,Flumatinib mesylate purchase,Flumatinib mesylate manufacturer,Flumatinib mesylate distributor,Flumatinib mesylate cost,Flumatinib mesylate buy,Flumatinib mesylate for sale