BAY 60-6583 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 910487-58-0 | Cat. No. | BCP45903 |
| Name | BAY 60-6583 | ||
| Synonyms | BAY-60-6583; BAY60-6583; | ||
| SMILES | C1CC1COC2=CC=C(C=C2)C3=C(C(=NC(=C3C#N)SCC(=O)N)N)C#N | ||
| Chemical Name | |||
| Formula | C19H17N5O2S | M. Wt | 379.44 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | BAY 60-6583 is a potent and selective adenosine A2B receptor agonist (EC50 = 2.83 nM for murine A2B receptor) displaying selectivity for A2B over A1, A2A and A3 receptors. BAY 60-6583 decreases fMLP-induced superoxide production in neutrophils at low concentrations (1-10 nM) and attenuates infarct size in a mouse model of myocardial ischemia, suggesting that it may be beneficial for the treatment of disorders in the coronary arteries, atherosclerosis and ischemia-reperfusion injury. | ||
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