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CAS No. | 58-55-9 | Cat. No. | BCP30664 |
Name | Theophylline | ||
Synonyms | Theo-24;1,3-Dimethyl-3,7-dihydro-1H-purine-2,6-dione ;1,3-Dimethylxanthine;1,3-dimethyl-xanthin; | ||
SMILES | CN1C2=C(C(=O)N(C1=O)C)NC=N2 | ||
Chemical Name | |||
Formula | C7H8N4O2 | M. Wt | 180.16 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Theophylline is a drug used in therapy for respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma under a variety of brand names. As a member of the xanthine family, it bears structural and pharmacological similarity to theobromine and caffeine. Like other methylated xanthine derivatives, theophylline is both a competitive nonselective phosphodiesterase inhibitor, which raises intracellular cAMP, activates PKA, inhibits TNF-alpha and inhibits leukotriene synthesis, and reduces inflammation and innate immunity nonselective adenosine receptor antagonist, antagonizing A1, A2, and A3 receptors almost equally, which explains many of its cardiac effects. |
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