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Gemcitabine Monophosphate Chemical Structure

Gemcitabine Monophosphate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP21656CAS No. :116371-67-6Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 116371-67-6 Cat. No. BCP21656
Name Gemcitabine Monophosphate
Synonyms 2'-Deoxy-2',2'-difluoro-5'-cytidylic Acid;
SMILES C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)(F)F
Chemical Name
Formula C9H12F2N3O7P M. Wt 343.18
Purity 98% Storage Store at 4-8°C
Description Gemcitabine Monophosphate is a gemcitabine derivative. It is an antineoplastic agent.Gemcitabine (Gem) is a deoxycytidine analog that is effective against pancreatic cancer and other malignancies following conversion to the 5'-O-mono-, di- and tri-phosphate forms. GemMP decreased tumor cell growth at concentrations ranging from 1 to 50 nM. GemMP is a potent cytotoxic agent that serves to induce apoptosis in association with increased Fas expression in cultured thyroid cancer cell lines.
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