Home   >  
Cell Cycle/DNA Damage
  >  
Antimetabolite
  >   RX3117
RX3117 Chemical Structure

RX3117

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP10720CAS No. ：865838-26-2Purity：98%
chem_1Get Quotation Now
 Tel: 0086-17754423994   or   orders@biochempartner.com
Real-Time Inquiry ×

* Required Fields.

Please complete the form below and you will get the price list in 1 minute.

Product name

  

* Applicant name

Catalog Number

  

* Institution/Company

* Email address

  

Phone number

Country

  

* Quantity Required

Remarks
Submit
Inquiry Online ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

  

* Applicant name

Catalog Number

  

* Institution/Company

* Email address

  

Phone number

Country

  

* Quantity Required

Remarks
Submit
Bulk Inquiry ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

  

* Applicant name

Catalog Number

  

* Institution/Company

* Email address

  

Phone number

Country

  

* Quantity Required

Remarks
Submit
  • Chemical Properties&Biological Activity
CAS No. 865838-26-2 Cat. No. BCP10720
Name RX3117
Synonyms RX-3117;RX 3117; TV1360; TV1360; TV 1360; Fluorocyclopentenylcytosine;
SMILES
Chemical Name
Formula C10H12FN3O4 M. Wt 257.22
Purity 98% Storage Store at 4-8°C
Description RX-3117, also known as TV-1360, is an orally available and potent DNA synthesis inhibitor with potential antineoplastic activity. Upon administration, the cytidine analogue RX-3117 is taken up by cells through a carrier-mediated transporter, phosphorylated by uridine cytidine kinase (UCK) and then further phosphorylated to its diphosphate (RX-DP) and triphosphate forms (RX-TP). The triphosphate form is incorporated into RNA and inhibits RNA synthesis. The diphosphate RX-DP is reduced by ribonucleotide reductase (RR) to dRX-DP; its triphosphate form (dRX-TP) is incorporated into DNA. In addition, RX-3117 also inhibits DNA methyltransferase 1 (DNMT1).
  • Quality Control&Technical Support
In the process of purchasing and using Biochempartner products, you can consult us if you have any problems: orders@biochempartner.com. We will try our best to solve all your doubts.

Recommend Products

More >

Tags:RX3117 supplier,RX3117 purchase,RX3117 manufacturer,RX3117 distributor,RX3117 cost,RX3117 buy,RX3117 for sale

0086-13720134139