Home   >  
Protease/Metabolic Enzyme
  >  
Proteasome
  >   Ixazomib Citrate
Ixazomib Citrate Chemical Structure

Ixazomib Citrate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP02411CAS No. :1201902-80-8Purity:98%
 Tel: 0086-17754423994   or   orders@biochempartner.com
Real-Time Inquiry ×

* Required Fields.

Please complete the form below and you will get the price list in 1 minute.

Product name

 

* Applicant name

Catalog Number

 

* Institution/Company

* Email address

 

Phone number

Country

 

* Quantity Required

Remarks

Inquiry Online ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

 

* Applicant name

Catalog Number

 

* Institution/Company

* Email address

 

Phone number

Country

 

* Quantity Required

Remarks

Bulk Inquiry ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

 

* Applicant name

Catalog Number

 

* Institution/Company

* Email address

 

Phone number

Country

 

* Quantity Required

Remarks

  • Chemical Properties&Biological Activity
CAS No. 1201902-80-8 Cat. No. BCP02411
Name Ixazomib Citrate
Synonyms MLN-9708;MLN9708;MLN 9708;
SMILES B1(OC(=O)CC(O1)(CC(=O)O)C(=O)O)C(CC(C)C)NC(=O)CNC(=O)C2=C(C=CC(=C2)Cl)Cl
Chemical Name
Formula C20H23BCl2N2O9 M. Wt 517.12
Purity 98% Storage Store at 4-8°C
Description MLN9708 is a selective, orally bioavailable, second-generation proteasome inhibitor. MLN9708 has a shorter proteasome dissociation half-life and improved pharmacokinetics, pharmacodynamics, and antitumor activity compared with bortezomib, which we believe plays an important role in its improved tissue distribution. MLN9708 has a larger blood volume distribution at steady state, and analysis of 20S proteasome inhibition and markers of the unfolded protein response confirms that MLN9708 has greater pharmacodynamic effects in tissues than bortezomib. MLN9708 is a second-generation small-molecule proteasome inhibitor being developed for the treatment of a broad range of human malignancies.Upon exposure to aqueous solutions or plasma, MLN9708 rapidly hydrolyzes to its biologically active form MLN2238.MLN2238 is the biologically active form of MLN9708.
  • Quality Control&Technical Support
In the process of purchasing and using Biochempartner products, you can consult us if you have any problems: orders@biochempartner.com. We will try our best to solve all your doubts.

Recommend Products

More >

Tags:Ixazomib Citrate supplier,Ixazomib Citrate purchase,Ixazomib Citrate manufacturer,Ixazomib Citrate distributor,Ixazomib Citrate cost,Ixazomib Citrate buy,Ixazomib Citrate for sale

0086-13720134139