Ixazomib citrate
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1239908-20-3 | Cat. No. | BCP16600 |
| Name | Ixazomib citrate | ||
| Synonyms | MLN9708; MLN-9708; MLN 9708;Ixazomib-prodrug; | ||
| SMILES | O=C(O)CC1(CC(O)=O)OB([C@@H](NC(CNC(C2=CC(Cl)=CC=C2Cl)=O)=O)CC(C)C)OC1=O | ||
| Chemical Name | |||
| Formula | C20H23BCl2N2O9 | M. Wt | 517.119 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | MLN9708, also known as ixazomib citrate, is a prodrug of Ixazomib (MMLN-2238). MLN9708 is an orally bioavailable second generation proteasome inhibitor (PI) with potential antineoplastic activity. MLN9708, after hydrolyzing to pharmacologically active MLN2238 (ixazomib), is a next-generation proteasome inhibitor with demonstrated preclinical and clinical antimyeloma activity. MLN9708, compared with bortezomib, has improved pharmacokinetics, pharmacodynamics, and antitumor activity in preclinical studies. | ||
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