BMX-IN-1 New
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| CAS No. | 1431525-23-3 | Cat. No. | BCP30306 |
| Name | BMX-IN-1 | ||
| Synonyms | BMX-IN1; BMX-IN 1;BMX kinase inhibitor; | ||
| SMILES | CC1=C(C=C(C=C1)N2C(=O)C=CC3=CN=C4C=CC(=CC4=C32)C5=CC=C(C=C5)NS(=O)(=O)C)NC(=O)C=C | ||
| Chemical Name | |||
| Formula | C29H24N4O4S | M. Wt | 524.59 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | BMX-IN-1 is a selective irreversible BMX inhibitor for prostate cancer. BMX-IN-1 can covalently modifies Cys496. BMX-IN-1 inhibits the proliferation of Tel-BMX-transformed Ba/F3 cells at two digit nanomolar concentrations but requires single digit micromolar concentrations to inhibit the proliferation of prostate cancer cell lines. MK2206, is able to potentiate BMX inhibitor's antiproliferation efficacy against prostate cancer cells. | ||
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