Vecabrutinib
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1510829-06-7 | Cat. No. | BCP29646 |
| Name | Vecabrutinib | ||
| Synonyms | SNS-062; SNS 062; SNS062; FP182; FP 182; FP-182; BSK-4841; BSK4841; BSK 4841; BIIB-062; BIIB062; BIIB 062; | ||
| SMILES | O=C1N([C@H]2CN(C3=NC=NC(N)=C3F)CC[C@@H]2C(N)=O)CCC[C@H]1NC4=CC(C(F)(F)F)=CC(Cl)=C4 | ||
| Chemical Name | |||
| Formula | C22H24ClF4N7O2 | M. Wt | 529.92 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Vecabrutinib, also known as SNS-062; FP-182, BSK-4841 and BIIB-062; is a potent, noncovalent, reversible BTK inhibitor that inhibits signaling through the BCR pathway. SNS-062 does not require interaction with BTK C481 for inhibitory activity. SNS-062 has improved PK properties over ibrutinib, including greater bioavailability and a longer half-life. SNS-062 may offer an alternative treatment option to patients with acquired resistance to ibrutinib. | ||
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