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Cerivastatin Chemical Structure

Cerivastatin

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP24254CAS No. ：145599-86-6Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 145599-86-6 Cat. No. BCP24254
Name Cerivastatin
Synonyms BAY-w-6228; BAY-w 6228; BAY-w6228;Rivastatin;
SMILES CC(C)C1=C(C(=C(C(=N1)C(C)C)COC)C2=CC=C(C=C2)F)C=CC(CC(CC(=O)O)O)O
Chemical Name
Formula C26H33FNNaO5 M. Wt 481.53
Purity 98% Storage Store at 4-8°C
Description Cerivastatin is a synthetic lipid-lowering agent. Cerivastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis. This agent lowers plasma cholesterol and lipoprotein levels, and modulates immune responses by suppressing major histocompatibility complex II on interferon gamma-stimulated, antigen-presenting cells such as human vascular endothelial cells. Muscle toxicity (myopathy and rhabdomyolysis) precludes the clinical use of this agent.
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