Pravastatin New

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP21480CAS No. ：81093-37-0Purity：98%

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CAS No.	81093-37-0	Cat. No.	BCP21480
Name	Pravastatin
Synonyms	CS-514;CS 514;CS514;
SMILES	CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC(CC(CC(=O)O)O)O)O
Chemical Name
Formula	C23H36O7	M. Wt	424.53
Purity	98%	Storage	Store at 4-8°C
Description	Pravastatin is an antilipemic fungal metabolite isolated from cultures of Nocardia autotrophica. It acts as a competitive inhibitor of HMG CoA reductase with IC50 of 5.6 μM. It is used in combination with diet, exercise, and weight loss for lowering cholesterol and preventing cardiovascular disease. It is a synthetic lipid-lowering agent. It lowers plasma cholesterol and lipoprotein levels, and modulates immune responses by suppressing major histocompatibility complex II on interferon gamma-stimulated, antigen-presenting cells such as human vascular endothelial cells. It is primarily used for the treatment of dyslipidemia and the prevention of cardiovascular disease. It is used to reduce LDL cholesterol and triglyceride levels and increase HDL cholesterol in the prevention of cardiovascular disease.