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Mevastatin Chemical Structure

Mevastatin

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP12101CAS No. ：73573-88-3Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 73573-88-3 Cat. No. BCP12101
Name Mevastatin
Synonyms Compactin;ML-236B;ML 236B;ML236B;
SMILES
Chemical Name
Formula C23H34O5 M. Wt 390.52
Purity 98% Storage Store at 4-8°C
Description Mevastatin induces apoptosis, arrests cancer cells in G1 phase and downregulates cdk 2, 4, and 6, cyclin D1 and E1, p21 and p27. Mevastatin suppresses TNF-induced NF-κB activation (IC50 = ~17 uM), which potentiates apoptosis in human myeloid leukemia cells and thus, may be useful in treating cancer.
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