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FGF401 Chemical Structure

FGF401

Data Sheet For research use only. Not for human use.
Cat. No. :BCP25143CAS No. :1708971-55-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1708971-55-4 Cat. No. BCP25143
Name FGF401
Synonyms FGF-401; FGF 401; Roblitinib;
SMILES CN1CCN(C(=O)C1)CC2=C(N=C3C(=C2)CCCN3C(=O)NC4=NC=C(C(=C4)NCCOC)C#N)C=O
Chemical Name
Formula C25H30N8O4 M. Wt 506.56
Purity 98% Storage Store at 4-8°C
Description FGF401 is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration, FGF401 binds to and inhibits the activity of FGFR4, which leads to an inhibition of tumor cell proliferation in FGFR4-overexpressing cells. FGFR4 is a receptor tyrosine kinase upregulated in certain tumor cells and involved in tumor cell proliferation, differentiation, angiogenesis, and survival.
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