SANT-1
Data Sheet
For research use only. Not for human use.
| Size | Price | Stock | Quotation Inquiry |
|---|---|---|---|
| 50.00 mg | Get quote | In-stock | Quotation Inquiry |
| 100.00 mg | Get quote | In-stock | Quotation Inquiry |
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| CAS No. | 304909-07-7 | Cat. No. | BCP08410 |
| Name | SANT-1 | ||
| Synonyms | SANT1;SANT 1; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C23H27N5 | M. Wt | 373.49 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | SANT-1 is a membrane permeable antagonist of the Shh signaling pathway by direct binding to Smo. This inhibition of Smo occurs equipotently by SANT-1 binding to both the oncogenic Smo and wild-type. When combined HDAC inhibitor SAHA, SANT-1 was able to suppress cellular proliferation and colony formation of Gemcitabine-resistant pancreatic adenocarcinoma cell lines Panc-1 and BxPC-3. | ||
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