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CAS No. | 344900-92-1 | Cat. No. | BCP37169 |
Name | FTI-2153 | ||
Synonyms | FTI2153; FTI 2153; | ||
SMILES | CC1=CC=CC=C1C2=C(C=CC(=C2)CNCC3=CN=CN3)C(=O)NC(CCSC)C(=O)OC | ||
Chemical Name | |||
Formula | C25H30N4O3S | M. Wt | 466.60 |
Purity | 98% | Storage | Store at 4-8°C |
Description | FTI-2153 is a potent farnesyltransferase inhibitor. FTI-2153 inhibits bipolar spindle formation during mitosis independently of transformation and Ras and p53 mutation status. FTI-2153 was reported to block bipolar spindle formation and chromosome alignment and causes prometaphase accumulation during mitosis of human lung cancer cells. |
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