MAZ51 New
Size | Price | Stock | Quotation Inquiry |
---|---|---|---|
500.00 mg | Get quote | In-stock | Quotation Inquiry |
1.00 g | Get quote | In-stock | Quotation Inquiry |
* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
CAS No. | 163655-37-6 | Cat. No. | BCP31595 |
Name | MAZ51 | ||
Synonyms | MAZ-51;MAZ 51; | ||
SMILES | CN(C)C1=CC=C(C2=CC=CC=C21)C=C3C4=CC=CC=C4NC3=O | ||
Chemical Name | |||
Formula | C21H18N2O | M. Wt | 314.38 |
Purity | 98% | Storage | Store at 4-8°C |
Description | MAZ51 is an indolinone that selectively antagonizes the activation of VEGFR3 by VEGFC (IC50 = 1 μM) without blocking VEGFC-mediated stimulation of VEGFR2.It does not inhibit ligand-induced autophosphorylation of EGFR, IGF-1R, or PDGFRβ.By preventing VEGFR3 activation, MAZ51 interferes with an autocrine loop involving the induced expression of the ligand VEGFC as well as VEGFA. It reduces proliferation and induces apoptosis in a variety of cancer cells in vitro and suppresses tumor growth in vivo. MAZ51 is used to study the role of VEGFR3 in endothelial and cancer cell function and survival. |
Recommend Products
More >-
-
Tyrphostin AG1433
Cat. No.:BCP48941
No.:168835-90-3
Product Details -
WAY-340935
Cat. No.:BCP46895
No.:737818-56-3
Product Details -
-
Ningetinib
Cat. No.:BCP46143
No.:1394820-69-9
Product Details -
Tivozanib hydrochloride hydrate
Cat. No.:BCP45190
No.:682745-41-1
Product Details -
-
-
Acrizanib
Cat. No.:BCP36110
No.:1229453-99-9
Product Details -
SAR131675
Cat. No.:BCP35024
No.:1433953-83-3
Product Details -
5Z-7-Oxozeaenol
Cat. No.:BCP34467
No.:253863-19-3
Product Details -
Donafenib
Cat. No.:BCP34023
No.:1130115-44-4
Product Details -
TAS-115 mesylate
Cat. No.:BCP34015
No.:1688673-09-7
Product Details -
-
Vandetanib trifluoroacetate
Cat. No.:BCP33121
No.:338992-53-3
Product Details -
-
-
-
-
(Z)-Guggulsterone
Cat. No.:BCP07472
No.:39025-23-5
Product Details
Tags:MAZ51 supplier,MAZ51 purchase,MAZ51 manufacturer,MAZ51 distributor,MAZ51 cost,MAZ51 buy,MAZ51 for sale