ERK5-IN-2 New
Data Sheet
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| CAS No. | 1888305-96-1 | Cat. No. | BCP32587 |
| Name | ERK5-IN-2 | ||
| Synonyms | ERK5-IN 2; ERK5 IN-2; | ||
| SMILES | C1=CC(=C(C(=C1)Br)C(=O)C2=CNC(=C2)C(=O)NC3=CN=CC=C3)F | ||
| Chemical Name | |||
| Formula | C17H11BrFN3O2 | M. Wt | 388.19 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50s of 0.82 μM, 3 μM for ERK5 and ERK5 MEF2D, respectively. ERK5-IN-2 does not interact with the BRD4 bromodomain. ERK5-IN-2 suppresses both tumor xenograft growth and basic fibroblast growth factor (bFGF) driven Matrigel plug angiogenesis. | ||
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