Tinoridine hydrochloride New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 25913-34-2 | Cat. No. | BCP30905 |
| Name | Tinoridine hydrochloride | ||
| Synonyms | Tinoridine HCl;Y-3642 hydrochloride; Nonflamin; Y-3642; Y 3642; Y3642; | ||
| SMILES | CCOC(=O)C1=C(SC2=C1CCN(C2)CC3=CC=CC=C3)N.Cl | ||
| Chemical Name | |||
| Formula | C17H20N2O2S.HCl | M. Wt | 352.87 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Tinoridine, also known as Y-3642, is a non-steroidal anti-inflammatory drug. Tinoridine, at concentrations from 5 microM up to 100 microM, produced a concentration-dependent inhibition on the simultaneous increases in lipid peroxide formation and renin release induced by 50 microM ascorbic acid in the renin granule fraction. On the other hand, indomethacin, hydrocortisone and prednisolone, which had no ability to inhibit the lipid peroxidation in the renin granule fraction, did not influence the release of renin from the granules. These results suggest that tinoridine suppresses renin release by inhibiting the oxidative disintegration of membranes of renin granules. | ||
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