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GSK461364 Chemical Structure

GSK461364

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP01720CAS No. ：929095-18-1Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 929095-18-1 Cat. No. BCP01720
Name GSK461364
Synonyms GSK-461364;GSK 461364;
SMILES
Chemical Name
Formula C27H28F3N5O2S M. Wt 543.6
Purity 98% Storage Store at 4-8°C
Description GSK461364 inhibits cancer cell line proliferation from multiple origins with minimal toxicity in nondividing human cells. [1] RNA silencing of WT p53 increases the antiproliferative activity of GSK461364. As many cancer therapies tend to be more effective in p53 WT patients, the higher sensitivity of p53-deficient tumors toward GSK461364 could potentially offer an opportunity to treat tumors that are refractory to other chemotherapies as well as early line therapy for these genotypes. GSK461364 i
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