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Lomeguatrib Chemical Structure

Lomeguatrib

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP07818CAS No. ：192441-08-0Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 192441-08-0 Cat. No. BCP07818
Name Lomeguatrib
Synonyms PaTrin-2;
SMILES
Chemical Name
Formula C10H8BrN5OS M. Wt 326.17
Purity 98% Storage Store at 4-8°C
Description Inhibitor of O6-methylguanine-DNA methyltransferase (MGMT); (IC50 = 0.009 μM in cell-free extracts from HeLa S3 cells); attenuates MGMT activity in vitro and in vivo. Enhances the antitumor activity of temozolomide in both human melanoma and MCF-7 xenografts.
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