RG108
Data Sheet
For research use only. Not for human use.
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| CAS No. | 48208-26-0 | Cat. No. | BCP06930 |
| Name | RG108 | ||
| Synonyms | N-Phthalyl-L-tryptophan; RG 108; RG-108; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C19H14N2O4 | M. Wt | 334.33 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | RG108 is a non-nucleoside DNA methyltransferase (DNMT) inhibitor. RG108 reactivates tumor suppressor gene expression (p16, SFRP1, secreted frizzled related protein-1, and TIMP-3) in tumor cells by DNA demethylation. RG108 also inhibits human tumor cell line (HCT116, NALM-6) proliferation and increased doubling time in culture. RG108 enhances the efficiency of induced pluripotent stem cell (iPS) generation. | ||
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