SGI-7079
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CAS No. | 1239875-86-5 | Cat. No. | BCP21014 |
Name | SGI-7079 | ||
Synonyms | SGI 7079; SGI707; | ||
SMILES | N#CCC1=CC=CC(C2=C3C(NC=C3C)=NC(NC4=CC=C(N5CCN(C)CC5)C(F)=C4)=N2)=C1 | ||
Chemical Name | |||
Formula | C26H26FN7 | M. Wt | 455.54 |
Purity | 98% | Storage | Store at 4-8°C |
Description | SGI-7079 is a potent and selective Axl inhibitor with potential anticancer activity. SGI-7079 effectively inhibited Axl activation in the presence of exogenous Gas6 ligand. SGI-7079 inhibited tumor growth in a dose dependent manner. Axl is a potential therapeutic target for overcoming EGFR inhibitor resistance. |
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