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CAS No. | 1196681-44-3 | Cat. No. | BCP13190 |
Related Products | 1025720-94-8(BMS-777607) | ||
Name | BMS 777607 | ||
Synonyms | BMS-777607;BMS777607; | ||
SMILES | CCOC1=C(C(=O)N(C=C1)C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C(C(=NC=C4)N)Cl)F | ||
Chemical Name | |||
Formula | C25H19ClF2N4O4 | M. Wt | 512.89 |
Purity | 98% | Storage | Store at 4-8°C |
Description | BMS 777607 is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50s of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively, and 40-fold more selective for Met-related targets than Lck, VEGFR-2, and TrkA/B, with more than 500-fold greater selectivity versus all other receptor and non receptor kinases. |
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