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BMS 777607 Chemical Structure

BMS 777607

Data Sheet For research use only. Not for human use.
Cat. No. :BCP13190CAS No. :1196681-44-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1196681-44-3 Cat. No. BCP13190
Related Products 1025720-94-8(BMS-777607)
Name BMS 777607
Synonyms BMS-777607;BMS777607;
SMILES CCOC1=C(C(=O)N(C=C1)C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C(C(=NC=C4)N)Cl)F
Chemical Name
Formula C25H19ClF2N4O4 M. Wt 512.89
Purity 98% Storage Store at 4-8°C
Description BMS 777607 is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50s of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively, and 40-fold more selective for Met-related targets than Lck, VEGFR-2, and TrkA/B, with more than 500-fold greater selectivity versus all other receptor and non receptor kinases.
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