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CAS号 | 1030123-90-0 | 货号 | BCP37859 |
中文名 | AEM1 | ||
英文名 | AEM1 | ||
中文别名 | |||
英文别名 | AEM-1; AEM 1; | ||
SMILES | C1OC2=C(O1)C=C(C=C2)CNC3=C4C(=CSC4=NC=N3)C5=CC=C(C=C5)F | ||
化学名称 | |||
分子式 | C20H14FN3O2S | 分子量 | 379.41 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer. It acts by broadly decreasing the expression of NRF2 controlled genes, sensitizing A549 cells to various chemotherapeutic agents, and inhibiting the growth of A549 cells in vitro and in vivo. |
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